Adalimumab: Uses & Side Effects

Adalimumab reduces the effects of a substance in the body that can cause inflammation. It is used to treat many inflammatory conditions in adults, such as ulcerative colitis, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, and a skin condition called hidradenitis suppurativa.

Adalimumab is also used in adults and children to treat Crohn’s disease, juvenile idiopathic arthritis, or uveitis. It may also be used for purposes not listed in this medication guide.

What do you need to know before taking adalimumab?

Adalimumab affects your immune system. You may get infections more easily, even serious or fatal infections.

Before or during treatment with adalimumab, tell your doctor if you have signs of infection such as fever, chills, aches, tiredness, cough, skin sores, diarrhea, or burning when you urinate.

You should not use this medicine if you are allergic to adalimumab. Moreover, Adalimumab should not be given to a child younger than 2 years old (or 6 years old if treating Crohn’s disease). Children using adalimumab should be current on all childhood immunizations before starting treatment.


Some drugs should not be used together with adalimumab. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with adalimumab, especially:

  • Abatacept, etanercept
  • Anakinra
  • Azathioprine, mercaptopurine
  • Certolizumab, golimumab, infliximab, rituximab

How should you use adalimumab?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Adalimumab is injected under the skin. A healthcare provider will teach you how to properly use adalimumab by yourself.

Stop using adalimumab if you have any signs of an infection. Call your doctor for instructions.

What are the side effects of adalimumab?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using adalimumab and call your doctor right away if you have any symptoms of lymphoma:

  • Fever, swollen glands, night sweats, general feeling of illness
  • Joint and muscle pain, skin rash, easy bruising or bleeding
  • Pale skin, feeling light-headed or short of breath, cold hands and feet
  • Pain in your upper stomach that may spread to your shoulder
  • Loss of appetite, feeling full after eating only a small amount, weight loss

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* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.