ANA Test – Negative, Positive

The ANA test is a sensitive screening test used to detect autoimmune diseases. Autoimmune diseases feature a misdirected immune system, and each of them has characteristic clinical manifestations that are used to make the precise diagnosis.

The interpretation or identification of a positive ANA test does not make a diagnosis. It simply suggests to the doctor to consider the possibility that an autoimmune disease is present.

ANAs can be found in approximately 5% of the normal population, usually in low titers (low levels). These people usually have no disease. Titers of 1:80 or lower are less likely to be significant. (ANA titers of less than or equal to 1:40 are considered negative.)

Even higher titers are often insignificant in patients over 60 years of age. Ultimately, the ANA result must be interpreted in the specific context of an individual patient’s symptoms, underlying medical conditions, and other test results. It may or may not be significant, even if positive, in a given individual.

Keywords: Antinuclear Antibody (ANA); Antinuclear Antibody Screen; FANA; Fluorescent Antinuclear Antibody

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.