Angiotensin-Converting Enzyme: Reference Range

Angiotensin-Converting Enzyme (ACE) is a test to help diagnose and monitor sarcoidosis.


Normal Results:

Normal values vary based on your age and the test method used. Adults have an ACE level less than 40 micrograms/L.


Meanings of the results:

  • A normal ACE level does not rule out sarcoidosis, as the disease can be in an inactive state without causing an elevated ACE level. Besides, chronic sarcoidosis tends to cause normal ACE levels too.
  • An increased ACE level means it’s likely (in 50% to 80% of cases) that there’s an active case of sarcoidosis.
  • When monitoring the condition over time,
    • the decreasing of ACE level from a high number indicates spontaneous or therapy-induced remission and a favorable prognosis;
    • the increasing of it indicates either an early disease process that is progressing or disease activity that is not responding to therapy.


Keywords: Angiotensin-Converting Enzyme (ACE), SACE, Serum Angiotensin Converting Enzyme

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.