Antiphospholipid Antibodies and Test Result

Antiphospholipid antibodies are a group of immune proteins (antibodies) that the body mistakenly produces against itself in an autoimmune response to phospholipids. Tests can detect these antibodies that increase the risk of excessive blood clotting.

Several tests are available, including:

  • Cardiolipin antibodies
  • Lupus anticoagulant assays
  • Beta-2 glycoprotein 1 antibodies

What does the test result mean?

A negative result means that the tested antibody was not present at the time of the test.

A positive result include different levels:

  • Low to moderate levels of one or more antiphospholipid antibodies. They may occur temporarily due to an infection or drug or may appear as a person ages.
  • Moderate to high levels of one or more antiphospholipid antibodies. They persist when tested again 12 weeks later, indicate the likely continued presence of that specific antibody.

If tests indicate the presence of the lupus anticoagulant and it persists when retested, then it is likely that the person is positive for the lupus anticoagulant.


Keywords: antiphospholipid antibodies(APA)

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.