CA 15-3 Test – Reference Range

The reference range of serum CA 15-3 is less than 30 U/mL.

The upper limit of the range varies depending on the laboratory and kit used for the test. Values obtained with different assay kits, methods, or laboratories cannot be used interchangeably.

In general, the higher the CA 15-3 level, the more advanced the breast cancer and the greater the amount of cancer present (tumor burden). CA 15-3 concentrations tend to increase as the cancer grows.

In metastatic breast cancer, the highest levels of CA 15-3 often are seen when the cancer has spread to the bones and/or the liver.

Mild to moderate elevations of CA 15-3 are seen in a variety of conditions, including cancer of the lung, pancreas, ovary, prostate, and colon as well as cirrhosis, hepatitis, and benign breast disorders and in a certain percentage of apparently healthy individuals.

The CA 15-3 elevations seen in non-cancerous conditions tend to be stable over time.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.