Cabozantinib : Uses & Sides Effects

Cabozantinib is used to treat advanced kidney cancer, or thyroid cancer that has spread to other parts of the body. Cabozantinib is also used to treat liver cancer in people who have been previously treated with sorafenib (Nexavar).

How should I take cabozantinib?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not use cabozantinib tablets in place of cabozantinib capsules. Take only the pill form your doctor has prescribed. Avoid medication errors by always checking the medicine you receive at the pharmacy.

Take cabozantinib on an empty stomach, at least 1 hour before or 2 hours after you eat anything.

Do not take this medicine with food.

Take this medicine with a full glass of water.

Do not crush, chew, or break a tablet, and do not open a capsule. Swallow the pill whole.

Your blood pressure will need to be checked often.

If you need surgery or dental work, stop taking cabozantinib at least 28 days ahead of time.

If you have stopped taking cabozantinib for any reason, talk with your doctor before you start taking it again.

Store at room temperature away from moisture and heat.

Precautions

You should not use cabozantinib if you are allergic to it.

Tell your doctor if you have:

  • an open wound on your skin (or a wound that is still healing);
  • bleeding problems (such as bloody or tarry stools, or coughing up blood or vomit that looks like coffee grounds);
  • high blood pressure;
  • liver disease;
  • a pre-existing dental problem.

You may need to have a negative pregnancy test before starting this treatment.

Cabozantinib may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using cabozantinib and for at least 4 months after your last dose. Tell your doctor if you think you might be pregnant.

You should not breast-feed while using this medicine, and for at least 4 months after your last dose.

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Cabozantinib may cause a perforation (a hole or tear) or a fistula (an abnormal passageway) within your stomach or intestines. Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.

Call your doctor at once if you have:

  • severe or ongoing vomiting or diarrhea;
  • bloody or tarry stools, cough with bloody mucus or vomit that looks like coffee grounds;
  • heavy menstrual bleeding, or any other bleeding that will not stop;
  • pain, tenderness, redness, swelling, blistering, or peeling skin on the palms of your hands or the soles of your feet;
  • confusion, headache, vision changes, thinking problems;
  • a seizure;
  • a light-headed feeling, like you might pass out;
  • jaw pain, tooth pain, mouth sores;
  • heart attack symptoms–chest pain or pressure, pain spreading to your jaw or shoulder, sweating;
  • signs of a stroke–sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
  • signs of a blood clot–chest pain, cough, trouble breathing, swelling or warmth in your arms or legs.

Your future doses of cabozantinib may be delayed or permanently discontinued if you have certain side effects.

Common side effects may include:

  • nausea, vomiting, stomach pain, loss of appetite;
  • diarrhea, constipation;
  • mouth sores or redness, changes in your sense of taste;
  • feeling tired;
  • weight loss;
  • abnormal liver function tests or other blood tests.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Keyword: cabozantinib.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.