Calcitonin, also known as thyrocalcitonin, is a 32-amino acid linear polypeptide hormone that is produced in humans primarily by the parafollicular cells of the thyroid gland. It acts to reduce blood calcium.
The calcitonin test is used to help diagnose and monitor C-cell hyperplasia, medullary thyroid cancer, and multiple endocrine neoplasia type 2 (MEN 2).
The reference range for calcitonin in blood is
- Male: 0～14ng/L
- Female: 0～28ng/L
The increased calcitonin in blood may indicate
- Medullary thyroid carcinoma
- Small cell lung carcinoma
- Breast carcinoma
- Gastrointestinal carcinoma
- Chronic renal dysfunction
- Renal failure
The decreased calcitonin in blood may indicate
- Mild or severe Hypothyroidism
- Menopause (female)