Canakinumab

Canakinumab is a monoclonal antibody that blocks certain proteins in the body that can affect inflammation and other immune responses. Canakinumab is used to treat certain types of periodic fever syndromes, sometimes called auto-inflammatory syndromes.

Canakinumab is used to treat the following periodic fever syndromes in adults and children who are at least 4 years old:

  • Cryopyrin-Associated Periodic Syndromes (CAPS), including Familial Cold Autoinflammatory Syndrome and Muckle-Wells Syndrome
  • Tumor Necrosis Factor Receptor Associated Periodic Syndrome (TRAPS)
  • Hyperimmunoglobulin D Syndrome (HIDS), also called Mevalonate Kinase Deficiency (MKD)
  • Familial Mediterranean Fever (FMF)

Canakinumab is also used to treat Sudden Juvenile Idiopathic Arthritis (SJIA) in children who are at least 2 years old.

 

Keyword: canakinumab.