Cefuroxime: Uses, Side Effects

Cefuroxime is a cephalosporin antibiotic. It works by fighting bacteria in your body.

Cefuroxime is used to treat many kinds of bacterial infections, including severe or life-threatening forms.

Cefuroxime may also be used for purposes not listed in this medication guide.

Before taking this medicine

Do not take this medicine if you are allergic to cefuroxime, or to other cephalosporin antibiotics.

To make sure cefuroxime is safe for you, tell your doctor if you have:

  • an allergy to penicillin;
  • kidney disease;
  • liver disease;
  • a history of intestinal problems, such as colitis;
  • diabetes; or
  • if you are malnourished.

The liquid form may contain phenylalanine. Talk to your doctor before using this form of cefuroxime if you have phenylketonuria (PKU).

This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Cefuroxime can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

Cefuroxime can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Cefuroxime is not approved for use by anyone younger than 3 months old.

Side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody;
  • jaundice (yellowing of the skin or eyes);
  • skin rash, bruising, severe tingling, or numbness;
  • seizure (black-out or convulsions);
  • kidney problems–little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • severe skin reaction–fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

  • diarrhea;
  • nausea, vomiting;
  • unusual or unpleasant taste in your mouth; or
  • diaper rash in an infant taking liquid cefuroxime.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

What other drugs will affect cefuroxime?

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • probenecid (Benemid);
  • a blood thinner such as warfarin (Coumadin, Jantoven); or
  • a diuretic or “water pill.”

This list is not complete. Other drugs may interact with cefuroxime, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.


Keyword: cefuroxime.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.