Clinical Trial- CPI-613 in Combination with Gemcitabine and Nab-paclitaxel - Pancreatic Cancer
This is an open-label study of CPI-613 in combination with gemcitabine and nab-paclitaxel for patients with locally advanced or metastatic pancreatic cancer never treated with systemic chemotherapy. The primary specific aim of the study is to find out the maximum tolerated dose (MTD) of CPI-613 when given in combination with gemcitabine/nab-paclitaxel for patients with locally advanced or metastatic pancreatic cancer.
| Study Type : | Interventional  (Clinical Trial) |
| Estimated Enrollment : | 24 participants |
| Intervention Model: | Single Group Assignment |
| Intervention Model Description: | This is a single arm, open-label study of CPI-613 in combination with gemcitabine and nab-paclitaxel for patients with locally advanced or metastatic pancreatic cancer |
| Masking: | None (Open Label) |
| Primary Purpose: | Treatment |
| Official Title: | A Phase I Study of CPI-613 in Combination With Gemcitabine and Nab-paclitaxel (Abraxane) for Patients With Locally Advanced or Metastatic Pancreatic Cancer |
| Actual Study Start Date : | October 19, 2017 |
| Estimated Primary Completion Date : | November 2018 |
| Estimated Study Completion Date : | January 2019 |
Contacts
| Contact: Nancy Ginder, BSN, OCN | 973-971-6608 | nancy.ginder@atlantichealth.org | |
| Contact: Rosemary Stefiniw, RN, MS, CCRC | 973-971-5990 | rosemary.stefiniw@atlantichealth.org |
Location
| United States, New Jersey | |
| Morristown Medical Center | Recruiting |
| Morristown, New Jersey, United States, 07960 | |
| Contact: Nancy Ginder, BSN, OCN Â Â 973-971-6608 Â Â nancy.ginder@atlantichealth.org | |
| Sub-Investigator: Joshua Strauss, MD | |
| Principal Investigator: Angela T Alistar, MD | |
| Overlook Medical Center | Recruiting |
| Summit, New Jersey, United States, 07901 | |
| Contact: Christopher Buck, BSN, MS Â Â 908-522-2043 Â Â christopher.buck@atlantichealth.org | |
| Sub-Investigator: Sophie D Morse, MD | |
| ClinicalTrials.gov Identifier: | NCT03435289 |
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