Clinical Trial - Pain Processing in Adults With Migraines - Migraine

Primary Objective of this study: To assess experimental heat pain responses (pain intensity, pain unpleasantness, pain catastrophizing, emotional reactivity) in migraineurs vs. healthy controls.

The current tools of migraine pain measurement are inadequate to distinguish the overall burden of suffering, as there is an over reliance on a single numerical pain score to represent the entire pain experience. Measuring and targeting the affective component, in addition to the sensory component of pain, may capture this discrepancy in disease burden.


Study Type: Interventional  (Clinical Trial)
Estimated Enrollment: 98 participants
Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Pain Processing in Adults With Migraines
Actual Study Start Date: January 2016
Estimated Primary Completion Date: July 2020
Estimated Study Completion Date: July 2020



Contact: Rebecca E Wells, MD, MPH 336-716-2357
Contact: Nancy Buchheimer 336-716-3961 Identifier: NCT02748577


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