Creatine phosphokinase (CPK) - normal, high, low

Creatine phosphokinase (CPK) is an enzyme in the body. It is found mainly in the heart, brain, and skeletal muscle.

The normal range of CPK is:

  • 10 to 120 micrograms per liter (mcg/L)

High levels of CPK usually indicate some sort of stress or injury to your heart or other muscles, since CPK leaks into your blood when muscle tissue is damaged. In lupus treatment, an elevated CPK may suggest muscle inflammation due to disease activity or an overlapping condition. CPK levels can also be high after strenuous exercise, so your doctor may wish to recheck your CPK after several days of rest.

A low serum CPK value is frequently found in patients with connective tissue diseases.



* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.