CRP & hs-CRP - Difference & Normal Range

CRP, or C-reactive protein, is also called “standard CRP”, the standard CRP is mainly used to diagnose inflammation. 

Within 6-8 hours of infection, CRP begins to rise, it usually peaks within 24-28 hours. The peak value can be several hundreds of times the normal value. CRP value drops quickly after effective treatment. CRP goes up in a bacteria or fungal infection, but in a viral infection, CRP value doesn’t go up. Doctors use CPR as the first indicator to determine the type of infection. 

CRP is also used in the diagnosis of cancer, auto-immune disease, and some others. 

The level of CRP is normally low. The standard CPR test measures it in the range from 10 to 1000 mg/L.

hs-CRP, is called high-sensitive CRP, it’s different from the standard CRP. The hs-CRP accurately detects lower levels of the protein and is used to evaluate individuals for risk of heart disease CVD. It measures CRP in the range from 0.5 to 10 mg/L.

According to the American Heart Association:

  • You are at low risk of developing cardiovascular disease if your hs-CRP level is lower than 1.0 mg/L.
  • You are at average risk of developing cardiovascular disease if your levels are between 1.0 mg/L and 3.0 mg/L.
  • You are at high risk for cardiovascular disease if your hs-CRP level is higher than 3.0 mg/L.


* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.