Dabigatran - Uses & Side Effects

What is dabigatran?

Dabigatran is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation. Dabigatran is used when the atrial fibrillation is not caused by a heart valve problem.

Dabigatran is also used after hip replacement surgery to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism).

Dabigatran is also used to treat DVT or pulmonary embolism (PE), and to lower your risk of having a repeat DVT or PE.

Dabigatran may also be used for purposes not listed in this medication guide.

Dabigatran side effects

Get emergency medical help if you have signs of an allergic reaction: hives; pain or tight feeling in your chest, wheezing, difficult breathing; swelling of your face, lips, tongue, or throat.

Also seek emergency medical attention if you have symptoms of a spinal blood clot: back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

Call your doctor at once if you have:

  • any bleeding that will not stop;
  • headache, weakness, dizziness, or feeling like you might pass out;
  • easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
  • easy bruising, unusual bleeding, purple or red spots under your skin;
  • blood in your urine or stools, black or tarry stools;
  • cough with bloody mucus or vomit that looks like coffee grounds;
  • pink or brown urine;
  • joint pain or swelling; or
  • heavy menstrual bleeding.

Common side effects may include:

  • stomach pain or discomfort;
  • indigestion; or
  • nausea, diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

Dabigatran dosing information

Usual Adult Dose for Deep Vein Thrombosis — Prophylaxis:

Recommended doses: 150 mg orally twice a day

Comments: Generally, the extent of anticoagulation does not need to be assessed with this drug; however, when necessary, use aPTT or ECT, and not INR to assess anticoagulant activity.

Uses: Reduction of risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation; treatment of deep venous thrombosis and pulmonary embolism in patients who have been treated with a parenteral anticoagulant for 5 to 10 days; reduction in the risk of recurrence of deep venous thrombosis and pulmonary embolism in patients who have been previously treated.

Keywords: dabigatran

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.