Diabetes-Related Autoantibodies

Diabetes-related autoantibodies are proteins produced by the immune system that have been shown to be associated with type 1 diabetes. Testing can detect the presence of one or more of these autoantibodies in the blood.

Four of the most common diabetes-related autoantibody tests include:

  • Islet Cell Cytoplasmic Autoantibodies (ICA)
  • Glutamic Acid Decarboxylase Autoantibodies (GADA)
  • Insulinoma-Associated-2 Autoantibodies (IA-2A)
  • Insulin Autoantibodies (IAA)

The normal results of above should be negative.

If ICA, GADA, and/or IA-2A are present in a person with symptoms of diabetes, the diagnosis of type 1 diabetes is confirmed.

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