EGFR Mutation Testing

EGFR mutation testing detects mutations in the EGFR gene in cancer tissue, and plays an very important role in determining whether EGFR-targeted tyrosine kinase inhibitors (TKI) are beneficial for treating the tumor.

The full name of EGFR is epidermal growth factor receptor.

An activating EGFR mutation of lung cancer indicates the effectiveness of EGFR-targeted TKI (tyrosine kinase inhibitor) in treating the tumor.

No activating EGFR mutation of lung cancer indicates no effectiveness of EGFR-targeted TKI (tyrosine kinase inhibitor) in treating the tumor (the cancer will not respond to TKI).

Keywords: EGFR Mutation Testing; Epidermal Growth Factor Receptor; Epidermal Growth Factor Receptor Mutation Analysis; erbB-1; HER-1

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