Estrogen Level Test

An estrogen test measures the level of estrogens in the blood or urine. Estrogen can also be measured in saliva using at-home test kit. Estrogens are a group of hormones that play a key role in the development of female physical features and reproductive functions, including the growth of breasts and the uterus, and regulation of the menstrual cycle. Men also make estrogen but in much smaller amounts.

There are many types of estrogens, but only three types are commonly tested:

  • Estrone, also called E1, is the main female hormone made by women after menopause. Menopause is a time in a woman’s life when her menstrual periods have stopped and she can’t become pregnant anymore. It usually starts when a woman is around 50 years old.
  • Estradiol, also called E2, is the main female hormone made by nonpregnant women.
  • Estriol, also called E3 is a hormone that increases during pregnancy.

Measuring estrogen levels can provide important information about your fertility (the ability to get pregnant), the health of your pregnancy, your menstrual cycle, and other health conditions.

Other names: estradiol test, estrone (E1), estradiol (E2), estriol (E3), estrogenic hormone test

What is it used for?

Estradiol tests or estrone tests are used to help:

  • Find out the reason for early or late puberty in girls.
  • Find out the reason for late puberty in boys.
  • Diagnose menstrual problems.
  • Find out the cause of infertility (the inability to get pregnant).
  • Monitor infertility treatments.
  • Monitor treatments for menopause.
  • Find tumors that make estrogen.

An estriol hormone test is used to:

  • Help diagnose certain birth defects, including Down syndrome, during pregnancy.
  • Monitor a high-risk pregnancy.

Why do I need an estrogen test?

You may need an estradiol test or an estrone test if you:

  • Are having trouble getting pregnant.
  • Are a woman of childbearing age who is not having periods or having abnormal periods.
  • Are a girl with early or delayed puberty.
  • Have symptoms of menopause, including hot flashes and/or night sweats.
  • Have vaginal bleeding after menopause.
  • Are a boy with delayed puberty.
  • Are a man showing female characteristics, such as the growth of breasts.

If you are pregnant, your health care provider may order an estriol test between the 15th and 20th week of pregnancy as part of a prenatal test called a triple screen test. It can find out if your baby is at risk for a genetic birth defect such as Down syndrome. Not all pregnant women need to get an estriol test, but it is recommended for women who have a higher risk of having a baby with a birth defect. You may be at a higher risk if you:

  • Have a family history of birth defects.
  • Are age 35 or older.
  • Have diabetes.
  • Have a viral infection during pregnancy.

What do the results mean?

If your estradiol or estrone levels are higher than normal, it may be due to:

  • A tumor of the ovaries, adrenal glands, or testicles
  • Cirrhosis
  • Early puberty in girls; delayed puberty in boys

If your estradiol or estrone levels are lower than normal, it may be due to:

  • Primary ovarian insufficiency, a condition that causes a woman’s ovaries to stop working before she is 40 years old
  • Turner syndrome, a condition in which a woman’s sexual characteristics don’t develop properly
  • An eating disorder, such as anorexia nervosa
  • Polycystic ovary syndrome, a common hormone disorder affecting childbearing women. It is one of the leading causes of female infertility.

If you are pregnant and your estriol levels are lower than normal, it may mean your pregnancy is failing or that there is a chance your baby might have a birth defect. If the test shows a possible birth defect, you will need more testing before a diagnosis can be made.

Higher levels of estriol may mean you will be going into labor soon. Normally, estriol levels go up about four weeks before you start labor.

If you have questions about your results, talk to your health care provider.

Keyword: estrogen level test.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.