FDA Approved Drugs and User Comments: DOFETILIDE

User Comments:


For Arrhythmia: “After many months of suffering from Afib and trying all possible meds my electrophysiologist put me on Tikosyn and after first dose in the hospital I immediately converted. That was over 4 years ago. I am on 500micrograms twice a day plus Carvedilol 2x and Xarelto. I have eliminated caffeine and wine, only drink wine spritzer after dinner. No Afib since beginning, now am on dofetilide, a generic version of Tikosyn. Other than a stuffy nose occasionally or being a little thirsty during night only very positive experience for me. Also, of course, the high cost of medication, even the generic version is still costly. I am a 73 years old woman and wonder if I have to stay on it for the rest of my life to feel normal.”

isei (taken for 2 to 5 years) October 16, 2017


Tikosyn (dofetilide) for Arrhythmia: “Been on 500mcg Tikosyn taken twice daily for 2 months. Went into sinus rhythm after 2nd dose in the hospital. Experienced headaches and some chest pressure. After one month I began getting indigestion daily, gained weight while eating less, have daily headaches, exceptional thirst, and fatigue. My cardiologist said to continue same dose, along with 25mg metoprolol and 20mg xarelto for another 3 months. With the quality of life being less than before, I don’t know if I can hold off that long.”

Sal22 October 12, 2017


Tikosyn (dofetilide) for Arrhythmia: “Due to Medicare requirements, I had to switch to Tikosyn when the Sotalol I’d been on for years wasn’t working. Cardiologist suggested an Ablation procedure but until I had tried the Tikosyn, Medicare wouldn’t approve the Ablation. The Tikosyn neither brought me out of the A-fib as they hoped nor has kept me out of A-fib. So to get the requirements all done, I have been in A-fib for approximately 2 months – unable to do much more than sit in a recliner all day – and I still have to wait another 2 weeks to be able to get the Ablation done. My ankles and feet have started swelling, so looking at another 3.5 hour trip to my cardiologist due to that side effect of the drug. Unimpressed!”

Lonniebear (taken for 1 to 6 months) May 8, 2017


Tikosyn (dofetilide) for Arrhythmia: “Put on Tikosyn (while in hospital) for 24 hours post cardiac ablation for A-fib. Doctors did not like the looks of the QT wave after 12 hours and reduced dosage by half. Doctors were still alarmed with EKG results after reduced dosage and 12 more hours; discontinued medication at that time. Next time someone tells me they want to put me on a medication so scary it requires extra days in the Hospital, more blood tests and EKGs in the middle of the night – and the possibility it could cause sudden cardiac arrest and death…… Decline! Just sayin.”

Lakath (taken for less than 1 month) April 28, 2017


For Arrhythmia: “Side effects for me are pain & weakness in right leg, knee, ankle. Also, have had some afib. My INR has been dropping. Also, on Coumadin. Have been on Dofetilide for 2 mos.”

Negative (taken for 1 to 6 months) February 28, 2017


Tikosyn (dofetilide) for Arrhythmia: “Went on Tikosyn 250 mcg twice daily for almost 5 years and it worked like 100%. No side effects that I was aware of. Did the ‘guy’ thing and took myself off of this medication. SR was good for almost 2 years and today I’m going back to the hospital for the 3 day stay. Always leery of oblation and cardioversion, but my cardiologist highly recommended the Tikosyn route once again. My wife is going to the hospital with me this morning… not as a visitor, but will try the Tikosyn route too! She has AF with a high pulse rate while my AF is the slower heartbeat type. Will check in in 3 days to let you know how well Tikosyn has done. We are both 74 years old and other than this AF thing, are in very good health.”

BobWL (taken for 2 to 5 years) December 12, 2016

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.