ZONISAMIDE: FDA Approved Drugs and User Comments

User Comments:

For Seizures: “First seizure at age 58 and a second 16 months later at which time was prescribed zonisamide. I was told I could step up from 25mg twice a day to 100mg twice a day. But I stopped at 50mg twice a day. No seizures since being on medication and am on ketogenic diet – good for the brain and have lost kilos.When I first started this medication it really wiped me out. I could barely get out of bed. I found that a Viatamin B12 shot miraculously restored me. I have a booster every couple of months.Discovered that zonisamide is contributing to loss of bone density – osteoporosis. Now on Prolia treatment with vitamin D and calcium supplements. Also yoga and gym. Healthiest and fittest I’ve ever been in my life!Reduced to 75mg in the evening only. Hope to reduce to 50mg next year.”

Meandering (taken for 1 to 2 years) February 26, 2018

For Seizures: “Started Zonisamide about a week ago and at first it was okay. I had a bit of mind fog and now I feel as if I have the flu, my head hurt constantly, even tho I was told to take my meds at night I couldn’t sleep for hours even though I was exhausted, I lose my breath easily, and get super anxious for no reason. Even worse I called my doctor and they won’t take me off of it. Side effects are AWEFUL.”

JessHayden101 February 22, 2018

Zonegran (zonisamide) for Migraine Prevention: “I just turned 19 and I’ve seen 3 neurologists, 4 neurosurgeons, and a epileptic specialist all in the last 6 months. None of them can really tell me what’s wrong with me but Zonegran has helped a lot with the hard hitting headaches. I still get dull “I can feel it” headaches almost everyday but nothing compared what I used to get. I don’t get any major side effects, sometimes I slur or jumble worlds but I can recover them quickly, if I take it on an empty stomach my thought process is cloudy but nothing major. Also, I was normal weight before but I’ve lost 15 pounds since I started this medication 3 months ago.”

Holly19 (taken for 1 to 6 months) February 14, 2018

For Migraine Prevention: “No effect on my migraines. First I got a blotchy rash on neck, then reg rash under my breasts and on bilat sides of my groin. If I don’t use vaginal cream every 1-2 days, I touch cant hardly touch it with a washclboth. There is a clear drainage here. The rest of my body, especially my back itches like crazy. The ends of a lot of my fingers are split and they are painful. They have been like this for almost 2 months. My appetite is suppressed and I’ve lost some weight.”

Goatie7219 (taken for 1 to 6 months) January 7, 2018

For Migraine Prevention: “Migraines started after my hysterectomy in 2010. They have worsened since to the point now they are at least 3 times a week and debilitating. Was on several maintenance meds including topamax which worked for a while but always stopped working over time. The topamax worked over a year but caused horrible buzzing in my head, which neuro prescribed amitryptilline for. That did nothing lol. Eventually I began seeing an awesome neuro P.A. who started me on zonisamide 100 mg, then upped to 200 mg after a month cause headaches were creeping back. Just this week I had to call him again for the same reason plus the buzzing has started again….sigh. still, zonisamide does seem to work well. I just need the right dose.”

FeverishDrmr (taken for 6 months to 1 year) December 28, 2017

For Migraine Prevention: “I feel ill on this drug. Headache, muscle aches, nausea, constipation, gait problems.”

Lucyhipp (taken for less than 1 month) December 28, 2017

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.