HE4, short for Human Epididymis Protein 4, is a type of protein produced by most (not all) epithelial ovarian cancer cells. So, HE4 Test is used to detect the progression of epithelial ovarian cancer and determine if it recurs after treatment.
HE4 Test results are usually interpreted in conjunction with the levels of CA-125, which is a type of protein found in ovarian cancer cells.
When HE4 levels and CA-125 levels both fall, it’s a sign that the treatment worked effectively.
Keywords: HE4; Human Epididymis Protein 4; Human Epididymis Protein 4 (HE4)