How Pulmonary Arterial Hypertension can be categorized?

Pulmonary hypertension is classified into five groups depending on its cause.

Group 1: Pulmonary Arterial Hypertension

  • Cause unknown, known as idiopathic pulmonary arterial hypertension
  • A specific gene mutation that can cause pulmonary hypertension to develop in families, also called heritable pulmonary arterial hypertension.
  • Certain drugs, such as diet drugs
  • Heart abnormalities present at birth, also called congenital heart disease
  • Other conditions, such as connective tissue disorders (HIV infection or chronic liver disease)

Group2: Pulmonary hypertension caused by left-sided heart disease

  • Left-sided valvular heart disease
  • Failure of the lower left heart chamber (left ventricle)

Group3: Pulmonary hypertension caused by lung disease

  • Chronic obstructive pulmonary disease, such as emphysema
  • Lung disease such as pulmonary fibrosis
  • Sleep apnea and other sleep disorders
  • Long-term exposure to high altitudes in people who may be at higher risk of pulmonary hypertension

Group4: Pulmonary hypertension caused by chronic blood clots

  • Chronic blood clots in the lungs (pulmonary emboli)

Group5: Pulmonary hypertension associated with other conditions that have unclear reasons why the pulmonary hypertension occurs

  • Blood disorders
  • Disorders that affect several organs in the body
  • Metabolic disorders
  • Tumors pressing against arteries 


How to Treat PAH?

For different types of Pulmonary Arterial Hypertension, it is treated with different methods.

  • Group1 Pulmonary Arterial Hypertension Medicines:

1)    Phosphodiesterase-5 inhibitors, such as sildenafil

2)    Prostanoids, such as epoprostenol

3)    Endothelin receptor antagonists, such as bosentan and ambrisentan

4)    Calcium channel blockers, such as diltiazem

  • Group 2 Pulmonary Hypertension

Treat conditions that affect the left ventricle

  • Group3 Pulmonary Hypertension

Oxygen Therapy is needed for Group3

  • Group4 Pulmonary Hypertension

Blood-thinning medicines

  • Group5 Pulmonary Hypertension

It depends on its causes

  • 1) For all types of Pulmonary Hypertension

2)   Diuretics, also called water pills. These medicines help reduce fluid buildup in your body, including swelling in your ankles and feet.

3)   Blood-thinning medicines. These medicines help prevent blood clots from forming or getting larger.

4)   Digoxin. This medicine helps the heart beat stronger and pump more blood. Digoxin sometimes is used to control the heart rate if abnormal heart rhythms, such as arterial fibrillation or atrial flutter, occur.

5)   Oxygen therapy. This treatment raises the level of oxygen in your blood.

6)    Physical activity. Regular activity may help improve your ability to be active. Talk with your doctor about a physical activity plan that’s safe for you.

You may also like: How to Treat PAH?


Related FAQs:

What is Diastolic Blood Pressure Number?

What is Systolic Blood Pressure Number?

Difference Between Essential Hypertension and Secondary Hypertension

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.