How To Diagnose and Treat Mononucleosis?


To diagnose mononucleosis, the following tests may be performed:

  • Physical exam. Your doctor may perform a physical examination to look for signs like swollen lymph nodes, tonsils, liver or spleen, and consider how these signs relate to the symptoms you describe.
  • Blood tests. Antibody tests and white blood cell count are two types of blood tests your doctor may provide.


Treatment mostly involves bed rest, good nutrition and drinking plenty of fluids.

Medications may be used to treat secondary infections. A streptococcal (strep) infection accompanies the sore throat of mononucleosis, a sinus infection, or an infection of your tonsils (tonsillitis) can be treat with antibiotics because they are bacterial infections. Amoxicillin and other penicillin derivatives are not recommended for people with mononucleosis because they may cause a rash.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.