How to Manage Endometrial Cancer Effectively?
Q:
How to manage endometrial cancer?
A:
Treatment option depends on stages of endometrial cancer. The common treatments are as follow:
- Stage 1 requires total abdominal hysterectomy with bilateral salpingo-oophorectomy. The role of lymphadenectomy is debated
- The use of progestogen in the treatment is also effective for stage IA endometrial cancer. It is an option for those women who want to preserve their fertility.
- In stage II, radical hysterectomy should be used with systematic pelvic node clearance. Lymphadenectomy is important for staging and as a guide for adjuvant therapy.
- Stage III and IV are best treated with maximal de-bulking surgery in those women with good performance status and tumor that be removed.
- Compared to open surgery, laparoscopic methods are undertaken with equivalent survival rates and better postoperative recovery rate.
- If surgery is not possible because of medical contra-indications, external beam radiotherapy may be used in this situation.
- Recurrence may respond to radiotherapy. Radical radiotherapy for local recurrence is effective in over half the cases
- Chemotherapy increases survival time after primary surgery by approximately 25% relative to radiotherapy in stage III and IV endometrial cancer.
- Systematic treatment of metastatic and relapsed disease may involve endocrine therapy or cytotoxic chemotherapy.
Keywords: endometrial cancer treatment, endometrial cancer treatment options
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* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.