How to Treat PAH?

For different types of Pulmonary Arterial Hypertension, it is treated with different methods.

  • Group1 Pulmonary Arterial Hypertension Medicines:

1)    Phosphodiesterase-5 inhibitors, such as sildenafil

2)    Prostanoids, such as epoprostenol

3)    Endothelin receptor antagonists, such as bosentan and ambrisentan

4)    Calcium channel blockers, such as diltiazem

  • Group 2 Pulmonary Hypertension

Treat conditions that affect the left ventricle

  • Group3 Pulmonary Hypertension

Oxygen Therapy is needed for Group3

  • Group4 Pulmonary Hypertension

Blood-thinning medicines

  • Group5 Pulmonary Hypertension

It depends on its causes

  • 1) For all types of Pulmonary Hypertension

2)   Diuretics, also called water pills. These medicines help reduce fluid buildup in your body, including swelling in your ankles and feet.

3)   Blood-thinning medicines. These medicines help prevent blood clots from forming or getting larger.

4)   Digoxin. This medicine helps the heart beat stronger and pump more blood. Digoxin sometimes is used to control the heart rate if abnormal heart rhythms, such as atrial fibrillation or atrial flutter, occur.

5)   Oxygen therapy. This treatment raises the level of oxygen in your blood.

6)    Physical activity. Regular activity may help improve your ability to be active. Talk with your doctor about a physical activity plan that’s safe for you.


The treatment varies from person to person. However, if the PAH is extremely severe, the doctors may suggest surgeries, such as lung transit or heart transplant.

You may also like: Categories of Pulmonary Hypertension

What is the treatment procedures for treating Pulmonary Arterial Hypertension?

  1. Your doctor will treat the cause of your condition.
  2. Oxygen therapy: most people also get treatment to improve their breathing, which can also help if you are short of breath and have low oxygen levels in your blood.
  3. If you have severe pulmonary hypertension, your doctor will prescribe medications called calcium channel blockers, which will lower your blood pressure in lungs and the rest of your body.
  4. If calcium channel blockers is not effective or enough, your doctor will recommend you to go to a specialized treatment center for more targeted therapies that can open up your narrowing blood vessels.

Options include:

  • Pills: ambrisentan (Letairis), bocentan (Tracleer), macitentan (Opsumit), riociguat (Adempas), selexipag (Uptravi), sildenafil (Revatio), tadalafil (Adcirca), treprostinil(Orenitram)
  • Inhalers: Iloprost tromethamine (Ventavis), treprostinil (Tyvaso)
  • IV drugs: epopostenol sodium , treprostinil
  1. In more severe cases, or if medicines can’t help, your doctor may recommend a lung transplant or arterial septostomy.


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* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.