Immunoreactive Trypsin Result

If an IRT level is elevated, a newborn may have cystic fibrosis (CF). If the IRT is elevated, a child or adult may have abnormal pancreatic enzyme production, pancreatitis, or pancreatic cancer.

However, IRT testing is not diagnostic; there are a fair number of false positives and problems other than cystic fibrosis and pancreatitis that can cause an elevated IRT. An elevated level must be followed with other testing.

When diagnosing cystic fibrosis, this may include another IRT test in a month, CF gene mutation testing, and/or sweat chloride testing. If the IRT level is not elevated, then it is likely that the newborn does not have CF.

However, if suspicion of CF is high and the infant has signs and symptoms consistent with CF, other testing for cystic fibrosis, such as sweat chloride and/or CF gene mutation testing, should be considered.

Keywords: Immunoreactive Trypsinogen; Immunoreactive Trypsinogen (IRT); IRT; Serum Trypsinogen; Trypsin-like Immunoreactivity

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.