Lenvatinib: Uses & Sides Effects

Lenvatinib is used to treat thyroid cancer, kidney cancer, liver cancer.

How is this medicine (Lenvatinib) best taken?

Use lenvatinib as ordered by your doctor. Read all information given to you. Follow all instructions closely.

Take lenvatinib at the same time of day.

Keep taking lenvatinib as you have been told by your doctor or other health care provider, even if you feel well.

To gain the most benefit, do not miss doses.

Take with or without food.

Swallow whole. Do not chew or crush.

If you have trouble swallowing lenvatinib, the capsule can be dissolved in a small glass of water or apple juice. Dissolve the capsule as you have been told or read the package insert. Do not crush or break. Talk with your doctor or pharmacist if you have questions.

After mixing, take your dose right away. Do not store for future use.

After drinking, rinse the rest of the drug in the glass with more juice or water and drink.

Have your urine checked as you have been told by your doctor.

Have blood work checked as you have been told by the doctor. Talk with the doctor.

You will need to have heart function tests while taking lenvatinib. Talk with the doctor.

This medicine may affect how wounds heal. If you need to have surgery, you may need to stop lenvatinib before surgery. Start taking it again after surgery as you have been told by your doctor. Talk with your doctor.

If diarrhea or throwing up happens, talk with the doctor. You will need to make sure to avoid dehydration and electrolyte problems.

Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.

What do I need to tell my doctor BEFORE I take Lenvatinib?

If you have an allergy to lenvatinib or any part of lenvatinib.

If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

If you have high blood pressure.

If you are taking any drugs that can cause a certain type of heartbeat that is not normal (prolonged QT interval). There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.

If you are breast-feeding. Do not breast-feed while you take lenvatinib and for 1 week after your last dose.

This is not a list of all drugs or health problems that interact with lenvatinib.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take lenvatinib with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Lenvatinib?

Tell all of your health care providers that you take lenvatinib. This includes your doctors, nurses, pharmacists, and dentists.

High blood pressure has happened with lenvatinib. Rarely, very bad health problems from high blood pressure have happened. Check your blood pressure as your doctor has told you.

A type of abnormal heartbeat (prolonged QT interval) can happen with lenvatinib. Call your doctor right away if you have a fast heartbeat, a heartbeat that does not feel normal, or if you pass out.

A very bad and sometimes deadly brain problem called posterior reversible encephalopathy syndrome (PRES) has happened with lenvatinib. Call your doctor right away if you have signs like feeling confused, lowered alertness, change in eyesight, loss of eyesight, seizures, or very bad headache.

Kidney problems have happened with lenvatinib. Sometimes, these have been deadly. Talk with the doctor.

Very bad and sometimes deadly bleeding problems have happened with lenvatinib. Talk with the doctor.

Call your doctor right away if you have any signs of bleeding problems, like bruising; black, tarry, or bloody stools; bleeding gums; blood in the urine; coughing up blood; cuts that take a long time to stop bleeding; feel dizzy; feeling very tired or weak; nosebleeds; pain or swelling; throwing up blood or throw up that looks like coffee grounds; or very bad headache.

Very bad and sometimes deadly holes in the GI (gastrointestinal) tract or fistulas have happened with lenvatinib. Talk with the doctor.

Very bad and sometimes deadly liver problems have happened with lenvatinib. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.

Very bad blood clots like heart attack have happened with lenvatinib. Call your doctor right away if you have signs of heart attack like chest pain or pressure; arm, back, neck, or jaw pain; or shortness of breath. Call your doctor right away if you have signs of stroke like confusion, numbness or weakness on 1 side of your body, very bad dizziness or headache, or change in speech or eyesight.

If you are 75 or older, use lenvatinib with care. You could have more side effects.

This medicine may affect fertility. Fertility problems may lead to not being able to get pregnant or father a child. Talk with the doctor.

This medicine may cause harm to the unborn baby if you take it while you are pregnant.

If you are able to get pregnant, a pregnancy test will be done to show that you are NOT pregnant before starting lenvatinib. Talk with your doctor.

Use birth control that you can trust to prevent pregnancy while taking lenvatinib and for 1 month after stopping lenvatinib.

If you get pregnant while taking lenvatinib or within 1 month after your last dose, call your doctor right away.

Side Effects

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Change in taste.
  • Constipation.
  • Cough.
  • Not hungry.
  • Diarrhea.
  • Dizziness.
  • Dry mouth.
  • Hair loss.
  • Headache.
  • Belly pain or heartburn.
  • Mouth pain.
  • Mouth irritation or mouth sores.
  • Muscle or joint pain.
  • Upset stomach or throwing up.
  • Feeling tired or weak.
  • Not able to sleep.
  • Change in voice.
  • Weight loss.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Keyword: lenvatinib.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.