Mesalamine: Uses & Side Effects

Mesalamine affects a substance in the body that causes inflammation, tissue damage, and diarrhea.

Mesalamine is used to treat mild to moderate ulcerative colitis. Mesalamine is also used to prevent the symptoms of ulcerative colitis from recurring.

Some brands of mesalamine are for use only in adults, and some brands are for use in children who are at least 5 years old.

Before taking this medicine

You should not use mesalamine if you are allergic to mesalamine, aspirin, sulfasalazine, or salicylates (such as Nuprin Backache Caplet, Kaopectate, KneeRelief, Pamprin Cramp Formula, Pepto-Bismol, Tricosal, Trilisate, and others).

Tell your doctor if you have ever had:

  • a blockage in your stomach or intestines (such as pyloric stenosis);
  • a skin condition such as eczema;
  • liver disease; or
  • kidney disease.

Side effects

Common side effects may include:

  • nausea, stomach pain, diarrhea, constipation;
  • runny or stuffy nose, sinus pain, sore throat;
  • flu-like symptoms;
  • headache, back pain;
  • rash; or
  • abnormal liver function tests.

Stop using mesalamine and call your doctor at once if you have:

  • severe stomach pain, cramping, bloody diarrhea;
  • fever, headache, skin rash;
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • kidney problems–little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath; or
  • liver problems–loss of appetite, upper stomach pain, tiredness, easy bruising or bleeding, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Keyword: mesalamine.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.