Metanephrine Test – Normal, High, Low

Normal urine levels of metanephrine and normetanephrine mean it is unlikely that the person tested has a catecholamine-secreting tumor.

This test is very sensitive, and these tumors are rare, so the negative predictive value of the test is very good. Elevated levels of metanephrine and normetanephrine in a person with signs and symptoms suggest the presence of a tumor.

The person will receive appropriate follow up to confirm the finding. Guidelines also suggest that imaging tests, such as MRI, be performed to locate the probable tumor.

If levels are elevated in someone who has been treated for a catecholamine-secreting tumor, it may be an indication that the treatment was not fully effective or that the tumor is recurring and appropriate follow up is needed.

Keyword: metanephrine

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.