New Guideline - Colorectal Cancer Screening Since 45

The American Cancer Society recommends that adults aged 45 years and older with an average risk of colorectal cancer(CRC) undergo regular screening with either a high‐sensitivity stool‐based test or a structural (visual) examination, depending on patient preference and test availability. As a part of the screening process, all positive results on noncolonoscopy screening tests should be followed up with timely colonoscopy. The recommendation to begin screening at age 45 years is a qualified recommendation. The recommendation for regular screening in adults aged 50 years and older is a strong recommendation.

The new guideline was published on 30 May 2018.

In the United States, colorectal cancer (CRC) is the fourth most common cancer diagnosed among adults and the second leading cause of death from cancer.

The ACS recommends (qualified recommendations) that:

1) average‐risk adults in good health with a life expectancy of more than 10 years continue CRC screening through the age of 75 years;

2) clinicians individualize CRC screening decisions for individuals aged 76 through 85 years based on patient preferences, life expectancy, health status, and prior screening history;

3) clinicians discourage individuals older than 85 years from continuing CRC screening.

The options for CRC screening are:

1) fecal immunochemical test annually;

2) high‐sensitivity, guaiac‐based fecal occult blood test annually;

3) multitarget stool DNA test every 3 years;

4) colonoscopy every 10 years;

5) computed tomography colonography every 5 years;

6) flexible sigmoidoscopy every 5 years.




* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.