Niacinamide is
LIKELY SAFE for most adults when taken by mouth. Unlike niacin, niacinamide does not cause flushing. However, niacinamide might cause minor adverse effects such as stomach upset, intestinal gas, dizziness, rash, itching, and other problems. When applied on the skin, niacinamide cream might cause mild burning, itching, or redness.
When doses of over 3 grams per day of niacinamide are taken, more serious side effects can happen. These include liver problems or high blood sugar.
Niacinamide is POSSIBLY SAFE when taken by mouth and appropriately in children or when applied to the skin of adults.
Special precautions & warnings:
Pregnancy and breast-feeding: Niacinamide is LIKELY SAFE for pregnant and breast-feeding women when taken in the recommended amounts. The recommended amount of niacin for pregnant or breast-feeding women is 30 mg per day for women under 18 years of age, and 35 mg for women over 18.
Allergies: Niacinamide can make allergies more severe because they cause histamine, the chemical responsible for allergic symptoms, to be released.
Diabetes: Niacinamide might increase blood sugar. People with diabetes who take niacinamide should check their blood sugar carefully.
Gallbladder disease: Niacinamide might make gallbladder disease worse.
Gout: Large amounts of niacinamide might bring on gout.
Liver disease: Niacinamide might increase liver damage. Don’t use it if you have liver disease.
Stomach or intestinal ulcers: Niacinamide might make ulcers worse. Don’t use it if you have ulcers.
Surgery: Niacinamide might interfere with blood sugar control during and after surgery. Stop taking niacinamide at least 2 weeks before a scheduled surgery.
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