Normal PSA Level Age Chart

Prostate-specific antigen, or PSA, is a protein produced by cells of the prostate gland. The PSA test measures the level of PSA in a man’s blood. PSA is produced by normal cells and malignant cells, it’s often elevated in men with prostate cancer, but a number of benign (not cancerous) conditions can also cause a man’s PSA level to rise.

Diseases associated with an elevated PSA level includes:

  • Prostatitis (inflammation of the prostate)
  • Benign prostatic hyperplasia (BPH) (enlargement of the prostate)
  • Prostate cancer
  • Urinary tract infection

A man’s PSA level generally rises by age.

Normal PSA Levels by Age Chart
AgeAsianAfricanCaucasian
(Years)(ng/mL)(ng/mL)(ng/mL)
40 – 490 – 2.00 – 2.00 – 2.5
50 – 590 – 3.00 – 4.00 – 3.5
60 – 690 – 4.00 – 4.50 – 4.5
70 – 790 – 5.00 – 5.50 – 6.5

There is no specific normal or abnormal level of PSA in the blood, and levels may vary over time in the same man. In the past, if a man had a PSA level above 4.0 ng/mL, doctors would often recommend a prostate biopsy to determine whether prostate cancer was present.

However, more recent studies have shown that some men with PSA levels below 4.0 ng/mL have prostate cancer and that many men with higher levels do not have prostate cancer.

According to statistics, a higher PSA score is linked to a higher probability of developing prostate cancer.

  • 15% of men with a PSA level less than 4 ng/ml develop prostate cancer.
  • 31% of men with PSA levels between 4 – 10 ng/ml develop prostate cancer.
  • 50% – 65% of men with psa scores over 10 ng/ml develop prostate cancer.

Scientists have been researching to find a way to distinguish cancerous from benign conditions and slow-growing cancers from fast-growing. None has been proved effective. Among all these measures, one of them is Age-specific PSA reference ranges.

Because a man’s PSA level tends to increase with age, it has been suggested that the use of age-specific PSA reference ranges may increase the accuracy of PSA tests. However, age-specific reference ranges have not been generally favored because their use may delay the detection of prostate cancer in many men.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.