Nucleated red blood cell (NRBC) is a mammalian RBC that contains a cell nucleus. It occurs in normal development as progenitor cells in the erythropoietic lineage and in pathological states.
Normally, NRBCs are found only in the circulation of fetuses and newborn infants. The normal range of NRBC in newborn infants is 0.01-0.02.
If NRBCs are found in adults, it may indicate some diseases including:
- Miliary tuberculosis
- Chronic hypoxemia