Phosphate salts containing sodium, potassium, aluminum, or calcium are
LIKELY SAFE for most people when taken by mouth, inserted into the rectum, or given intravenously (by IV) appropriately and short-term. Phosphate salts should only be used intravenously (by IV) under the supervision of a physician.
Phosphate salts (expressed as phosphorous) are POSSIBLY UNSAFE when taken in doses higher than 4 grams per day for adults younger than 70 years of age and 3 grams per day for people who are older.
Regular long-term use can upset the balance of phosphates and other chemicals in the body and should be monitored by a healthcare professional to avoid serious side effects. Phosphate salts can irritate the digestive tract and cause stomach upset, diarrhea, constipation, headache, tiredness, and other problems.
Do not confuse phosphate salts with substances such as organophosphates, or with tribasic sodium phosphates and tribasic potassium phosphates, which are very poisonous.
Special precautions & warnings:
Pregnancy and breast-feeding: Phosphate salts from dietary sources are LIKELY SAFE for pregnant or breast-feeding women when used at the recommended allowances of 1250 mg daily for mothers between 14-18 years of age and 700 mg daily for those over 18 years of age. Other amounts are POSSIBLY UNSAFE and should only be used with the advice and ongoing care of a healthcare professional.
Children: Phosphate salts are LIKELY SAFE for children when used at the recommended daily allowances of 460 mg for children 1-3 years of age; 500 mg for children 4-8 years of age; and 1250 mg for children 9-18 years of age. Phosphate salts are POSSIBLY UNSAFE if the amount of phosphate consumed (expressed as phosphorous) exceeds the tolerable upper intake level (UL). The ULs are 3 grams per day for children 1-8 years; and 4 grams per day for children 9 years and older.
Heart disease: Avoid using phosphate salts that contain sodium if you have heart disease.
Fluid retention (edema): Avoid using phosphate salts that contain sodium if you have cirrhosis, heart failure, or other conditions that can cause edema.
High levels of calcium in the blood (hypercalcemia): Use phosphate salts cautiously if you have hypercalcemia. Too much phosphate could cause calcium to be deposited where it shouldn’t be in your body.
High levels of phosphate in the blood: People with Addison’s disease, severe heart and lung disease, kidney disease, thyroid problems, or liver disease are more likely than other people to develop too much phosphate in their blood when they take phosphate salts. Use phosphate salts only with the advice and ongoing care of a healthcare professional if you have one of these conditions.
Kidney disease: Use phosphate salts only with the advice and ongoing care of a healthcare professional if you have kidney problems.
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