Can Polycystic Kidney Disease Result in Liver Disease?

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Q:
Can polycystic kidney disease result in liver disease?

A:
The answer is yes. Autosomal dominant polycystic kidney disease usually results in the growth of liver cysts. In other cases, the patient may also develop liver fibrosis and enlargement of the biliary tract.

Although most patients with ADPKD have no symptoms for liver disease, in some cases ADPKD does affect the health of the patient’s liver. As liver function declines, the disease will severely influence the patient’s quality of life. In addition, some patients may develop acute complications that can be life-threatening.

The cause of liver disease on PKD patients is still unclear. But scientific research has shown that polycystic liver disease is related to ADPKD and is linked either to PKD1 gene or to PKD2 gene.

Keywords: polycystic kidney liver disease, polycystic liver kidney disease.

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