Posaconazole: Uses, Side Effects

Posaconazole is an antifungal medicine that fights certain infections caused by fungus.

Posaconazole is used to prevent fungal infections in people who have a weak immune system resulting from certain treatments or conditions (such as chemotherapy, stem cell transplantation, HIV infection, and others).

Posaconazole oral suspension (liquid) is used to treat oral thrush (yeast infection of the mouth) in adults and children who are at least 13 years old.

Important Information

You should not use posaconazole together with: atorvastatin, lovastatin, simvastatin, pimozide, quinidine, sirolimus, or an ergot medicine (dihydroergotamine, ergotamine, ergonovine, or methylergonovine).

You should not use posaconazole if you are allergic to posaconazole or similar antifungals such as clotrimazole, fluconazole, ketoconazole, miconazole, voriconazole, and others.

Side Effects

Commonly reported side effects of posaconazole include:

  • cytomegalovirus disease,
  • febrile neutropenia,
  • herpes simplex infection,
  • abdominal pain,
  • anemia,
  • arthralgia,
  • back pain,
  • constipation,
  • cough,
  • diarrhea,
  • dizziness,
  • dyspepsia,
  • epistaxis,
  • fatigue,
  • fever,
  • headache,
  • hyperbilirubinemia,
  • hyperglycemia,
  • hypertension,
  • hypokalemia,
  • hypotension,
  • insomnia,
  • lower extremity edema,
  • mucositis,
  • musculoskeletal pain,
  • nausea,
  • neutropenia,
  • petechia,
  • pharyngitis,
  • pruritus,
  • rigors,
  • skin rash,
  • tachycardia,
  • thrombocytopenia,
  • vaginal hemorrhage,
  • vomiting,
  • anorexia,
  • and bacteremia.

Other side effects include:

  • upper respiratory tract infection,
  • anxiety, asthenia,
  • edema,
  • hypocalcemia,
  • and prolonged qt interval on ecg.


Keyword: posaconazole.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.