Simponi: Uses & Side Effects

Simponi is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or ulcerative colitis. It reduces the effects of a substance in the body that can cause inflammation.

Before You Take Simponi

You should not use Simponi if you are also using abatacept or anakinra.

Simponi affects your immune system. You may get infections more easily, even serious or fatal infections. Call your doctor if you have a fever, chills, aches, tiredness, cough, skin sores, diarrhea, or burning when you urinate.

Serious and sometimes fatal infections may occur during treatment with Simponi, especially if you also use other medications that can weaken your immune system.

If you have ever had tuberculosis or hepatitis B, Simponi can cause these conditions to come back or get worse. You should be tested for these conditions before you start using this medicine.

Some people using Simponi have developed a rare fast-growing type of lymphoma (cancer) that affects the liver, spleen, and bone marrow, and it can be fatal. This has occurred mostly in teenage boys and young men using golimumab.

Simponi Side Effects

Get emergency medical help if you have signs of an allergic reaction to Simponi: hives, itching; nausea; chest pain, difficulty breathing; swelling of your face, lips, tongue, or throat.

You may get infections more easily, even serious or fatal infections. Call your doctor right away if you have signs of infection such as:

  • Fever, chills, sore throat, mouth sores, feeling light-headed
  • Cough, shortness of breath
  • Night sweats, loss of appetite, weight loss, and feeling very tired
  • Skin sores, warmth, or redness
  • Diarrhea, stomach pain, coughing up blood
  • Increased urination or burning when you urinate

Also call your doctor at once if you have:

  • Skin growths or changes in skin appearance
  • Shortness of breath with swelling of your ankles or feet
  • Vision changes
  • Numbness or tingly feeling, weakness in your arms or legs
  • Pale skin, easy bruising or bleeding
  • Liver problems – right-sided upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
  • New or worsening symptoms of lupus – muscle or joint pain, and a skin rash on your cheeks or arms that worsens in sunlight
  • Signs of psoriasis – red or scaly patches of skin, flaking, pus

Use Simponi exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Keywords: Simponi

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.