Sorafenib: Uses & Sides Effects
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Sorafenib is used to treat liver cancer,
thyroid cancer, or kidney cancer.
How should I take sorafenib?
Follow all directions on your prescription
label and read all medication guides or instruction sheets. Use the medicine
exactly as directed.
Take sorafenib on an empty stomach, at
least 1 hour before or 2 hours after eating.
Your blood pressure will need to be checked
often.
If you need surgery or dental work, tell
the surgeon or dentist ahead of time that you are using sorafenib. You may need
to stop using the medicine for a short time.
Store at room temperature away from
moisture and heat.
Precautions
You should not use sorafenib if you are
allergic to it, or if you have squamous cell lung cancer and you are being
treated with carboplatin and paclitaxel.
Tell your doctor if you have ever had:
- heart disease, high blood pressure;
- long QT syndrome (in you or a family member);
- bleeding problems;
- an electrolyte imbalance (such as abnormal levels of calcium,
magnesium, or potassium in your blood).
Sorafenib can harm an unborn baby or cause
birth defects if the mother or the father is using sorafenib.
- If you are a woman, do
not use sorafenib if you are pregnant. You may need to have a negative
pregnancy test before starting this treatment. Use effective birth control to
prevent pregnancy while you are using this medicine and for at least 6 months
after your last dose.
- If you are a man, use
effective birth control if your sex partner is pregnant or is able to get
pregnant. Keep using birth control for at least 3 months after your last dose.
Tell your doctor right away if a pregnancy
occurs while either the mother or the father is using sorafenib.
Do not breast-feed while using this
medicine, and for at least 2 weeks after your last dose.
Side
Effects
Get emergency medical help if you have
signs of an allergic reaction (hives, difficult breathing, swelling in your
face or throat) or a severe skin reaction (fever, sore throat, burning eyes,
skin pain, red or purple skin rash with blistering and peeling).
Get emergency medical help if you have
symptoms of a heart attack or heart failure: chest pain, fast heartbeats,
sweating, nausea, trouble breathing, feeling light-headed, or swelling around
your midsection or in your lower legs.
Call your doctor at once if you have:
- fast or pounding heartbeats, fluttering in your chest, shortness of
breath, and sudden dizziness (like you might pass out);
- easy bruising or bleeding (nosebleeds, bleeding gums);
- heavy menstrual periods or unusual vaginal bleeding;
- pain, redness, swelling, rash, blisters or peeling in the palms of
your hands or the soles of your feet;
- fever with nausea, vomiting, or severe stomach pain
- any wound that will not heal;
- liver problems–loss of appetite, stomach pain (upper right side),
nausea, dark urine, clay-colored stools, jaundice (yellowing of the skin or
eyes);
- signs of bleeding inside your body–pink or brown urine, abnormal
vaginal bleeding, bloody or tarry stools, coughing up blood or vomit that looks
like coffee grounds.
Common side effects may include:
- bleeding;
- feeling tired;
- vomiting, diarrhea, nausea, stomach pain;
- high blood pressure;
- rash;
- weight loss, thinning hair.
Always consult your healthcare provider to
ensure the information displayed on this page applies to your personal
circumstances.
Keyword: sorafenib.
* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.
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