Study Shows Aspirin Fight Against Bowel Tumor

Aspirin can help you to stave off bowel cancer by blocking a key process linked to tumor formation, this has been found by experts from the University’s Cancer Research UK Edinburgh Centre.

Regular use of aspirin is known as a painkiller, and recently there were a few results coming out about aspirin’s effect to reduce a person’s risk of developing colon cancer from various research teams around the world. But the drug’s tumour fighting properties have not been well understood.

Researchers at the University of Edinburgh focused on a structure found inside cells called the nucleolus. Activation of the nucleolus is known as a key step to drive tumor formation.

The team at the University’s Cancer Research UK Edinburgh Centre tested the effects of aspirin on cells grown in the lab and on tumour biopsies removed from colon cancer patients.

They found that aspirin blocks a key molecule called TIF-IA, which is essential for the nucleolus to function.

Not all colon cancer patients respond to aspirin but the researchers say their findings could help pinpoint those most likely to benefit.

Aspirin is a blood thinner which has side effects including internal bleeding. There is a concern for long-term use of aspirin. The researchers will keep working on the development of new, safer therapies that mimic aspirin’s effects.


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