Trametinib: Uses & Sides Effects

Trametinib is used to treat skin cancer, lung cancer.

How is this medicine (Trametinib) best taken?

Use trametinib as ordered by your doctor. Read all information given to you. Follow all instructions closely.

Take trametinib at the same time of day.

Take on an empty stomach. Take 1 hour before or 2 hours after meals.

To gain the most benefit, do not miss doses.

Keep taking trametinib as you have been told by your doctor or other health care provider, even if you feel well.

What do I need to tell my doctor BEFORE I take Trametinib?

If you have an allergy to trametinib or any other part of trametinib.

If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

If you are breast-feeding. Do not breast-feed while you take trametinib or for 4 months after your last dose.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take trametinib with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Trametinib?

Tell all of your health care providers that you take trametinib. This includes your doctors, nurses, pharmacists, and dentists.

Sometimes, dabrafenib is taken with trametinib. If you are taking dabrafenib with trametinib, be sure you know the side effects that can happen with each drug. When these drugs are taken together, the chance of certain side effects may be raised. These side effects can be very bad and sometimes deadly. This includes bleeding, bleeding in the brain, blood clots, eye problems, fever, heart problems (like heart failure), high blood sugar, other cancers, and skin problems. Talk with your doctor about the chance of side effects with your drugs.

High blood pressure has happened with trametinib. Have your blood pressure checked as you have been told by your doctor.

Have blood work checked as you have been told by the doctor. Talk with the doctor.

Have your eye pressure and eyesight checked as you have been told by the doctor.

Blood clots have happened with trametinib. Tell your doctor if you have ever had a blood clot. Talk with your doctor.

Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.

It is common to get a rash with trametinib but other skin reactions may also happen. Sometimes, these rashes and skin reactions can be very bad and may need treatment in the hospital. Call your doctor right away if you have acne, skin redness, or a skin rash that bothers you or does not go away. Call your doctor right away if you have redness or irritation of the palms of hands or soles of feet.

Very bad eye problems have happened with trametinib. Sometimes, this has led to loss of eyesight. Call your doctor right away if you have blurred eyesight, loss of eyesight, or other changes in eyesight. Call your doctor right away if you see color dots or halos or if bright lights bother you.

A bowel problem (colitis) and holes in the bowel have happened with trametinib. Sometimes, these have been deadly. Call your doctor right away if you have diarrhea, stomach pain or cramps, fever, or very upset stomach.

If you are 65 or older, use trametinib with care. You could have more side effects.

This medicine may cause fertility problems. This may affect being able to have children. Talk with the doctor.

This medicine may cause harm to the unborn baby if you take it while you are pregnant.

Use birth control that you can trust to prevent pregnancy while taking trametinib and for 4 months after your last dose.

If you get pregnant while taking trametinib or within 4 months after your last dose, call your doctor right away.

Side Effects

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Dry skin.
  • Change in nails.
  • Mouth irritation or mouth sores.
  • Upset stomach or throwing up.
  • Feeling tired or weak.
  • Not hungry.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Keyword: trametinib.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.