Viberzi: Uses & Side Effects

Viberzi (eluxadoline) works directly in your intestines to slow the movement of food during digestion. Eluxadoline also makes the nerves in your intestines less sensitive to stimulation.

Viberzi is used to treat irritable bowel syndrome when the main symptom is diarrhea.

Viberzi may also be used for purposes not listed in this medication guide.


Before taking this medicine

You should not use Viberzi if you are allergic to eluxadoline, or if you have:

  • severe constipation or a blockage in your intestines;
  • a history of gallbladder obstruction, or if your gallbladder has been removed;
  • digestive problems caused by a muscle valve called the sphincter of Oddi (SFINK-ter of OD-dee);
  • severe liver disease;
  • a pancreas disorder; or
  • a habit of drinking more than 3 alcoholic beverages per day.

Tell your doctor if you have ever had liver disease.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.

Viberzi is not approved for use by anyone younger than 18 years old.


Side effects

Get emergency medical help if you have signs of an allergic reaction to Viberzi: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking this medicine and call your doctor at once if you have:

  • new or worsening stomach pain (may be severe);
  • nausea and vomiting;
  • severe constipation;
  • constipation lasting longer than 4 days; or
  • severe pain in your upper stomach spreading to your back.

Side effects may be more likely in older adults.

Common Viberzi side effects may include:

  • constipation;
  • nausea; or
  • stomach pain.


Keywords: Viberzi; eluxadoline.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.