Vitamin B6 is
LIKELY SAFE for most people when used appropriately.
Vitamin B6 is POSSIBLY SAFE when taken by mouth in amounts greater than the recommended dietary allowance. In some people, vitamin B6 might cause nausea, vomiting, stomach pain, loss of appetite, headache, tingling, sleepiness, and other side effects.
Long-term use of high doses of vitamin B6 and when vitamin B6 is given as a shot into the muscle is POSSIBLY UNSAFE. When used orally in high doses it might cause certain brain and nerve problems. When given as a shot into the muscle it might cause muscle problems.
Special precautions & warnings:
Pregnancy and breast-feeding: Vitamin B6 is LIKELY SAFE for pregnant women when taken under the supervision of their healthcare provider. It is sometimes used in pregnancy to control morning sickness. High doses are UNSAFE. High doses can cause newborns to have seizures.
Vitamin B6 is LIKELY SAFE for breast-feeding women when used in amounts not larger than 2 mg per day (the recommended dietary allowance). Avoid using higher amounts. Not enough is known about the safety of vitamin B6 at higher doses in breast-feeding women.
Procedures to widen narrowed arteries (angioplasty). Using vitamin B6 along with folic acid and vitamin B12 intravenously (by IV) or by mouth might worsen narrowed arteries. Vitamin B6 should not be used by people recovering from this procedure.
Diabetes. Using vitamin B6, folic acid, and vitamin B12 might increase the risk of cancer in people with diabetes and a recent stroke. Vitamin B6 should not be used by patients with diabetes that have had a recent stroke.
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