What are Paraganglioma and Pheochromocytoma?

What are paraganglioma and pheochromocytoma?

Paraganglioma is a rare cancer. It originates in the nerve cells of the adrenal glands, organs on top of each kidney that produce important hormones. Paraganglioma that develops in the center of the adrenal gland is pheochromocytoma.

Each year, 2 to 8 people per million have paraganglioma and pheochromocytoma across the world. 10% of all cases occur in children. In both adults and children, pheochromocytoma is more common than paraganglioma.

By now, no known environmental, dietary, or lifestyle risk factors have something to do wiith these cancers. However, paraganglioma and pheochromocytoma can be hereditary diseases: one study reported that about 41% of patients with one of these diseases in the U.S. carry inherited genetic mutations, which increases the risk of malignancy. When the cancer spreads to other parts of the body, only 44% of patients survive 5 years after their diagnosis.

Keyword: paraganglioma pheochromocytoma



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