What Are the Basics of Ewing Sarcoma?

What is Ewing sarcoma?

Ewing sarcoma or Ewing’s sarcoma is a malignant small, round, blue cell tumor that grows in your bones or the soft tissue around your bones, such as cartilage or the nerves.

It is a rare type of childhood cancer that is most frequently found in children and adolescents between the ages of 10 and 20 years old.

What are the signs and symptoms of Ewing sarcoma?

Signs and symptoms of Ewing sarcoma include:

  • Pain, swelling or tenderness near the affected area
  • Bone pain, which may worsen at night or with physical activity
  • Unexplained tiredness
  • Fever with no known cause
  • Unintended weight loss
  • Broken bone with no known cause

What are the causes of Ewing sarcoma?

The causes of Ewing sarcoma remain unknown. Although Ewing sarcoma arises from specific types of cells, it doesn’t appear to be inherited.

But some statistics show that genetic exchange between chromosomes can cause cells to become cancerous. About 85% cases of Ewing sarcoma are the result of a translocation between chromosomes 11 and 22, which fuses the EWS gene f chromosome 22 to the FL 11 gene of chromosome 11, according to Wikipedia.

How to treat Ewing sarcoma?

Treatment options for Ewing sarcoma may include:

  • Chemotherapy
  • Surgery
  • Radiation therapy
  • Clinical trials

What is the survival rate for Ewing sarcoma?

According to Wikipedia, five-year survival for localized disease is 70% to 80% when treated with chemotherapy. Prior to the use of multi-drug chemotherapy, long-term survival was less than 10%. The development of multi-disciplinary therapy with chemotherapy, irradiation, and surgery has increased current long-term survival rates in most clinical centers to greater than 50%. However, some sources state it is 25–30%.

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* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.