What Are the Risk Factors and Symptoms of Ankylosing Spondylitis?

Q:
What are the risk factors and symptoms of ankylosing spondylitis?

A:
Risk factors of ankylosing spondylitis include:

  • Age. Onset generally occurs in late adolescence or early adulthood.
  • Sex. Men are more likely to develop ankylosing spondylitis than are women.
  • Heredity. Most people who have ankylosing spondylitis have the HLA-B27 gene. But many people who have this gene never develop ankylosing spondylitis.

Early signs and symptoms of ankylosing spondylitis might include pain and stiffness. The areas most commonly affected are:

  • The back of your heel
  • The cartilage between your breastbone and ribs
  • The joint between the base of your spine and your pelvis (sacroiliac)
  • The places where your tendons and ligaments attach to bones (entheses), mainly in your spine, but sometimes along
  • The vertebrae in your lower back
  • Your hip and shoulder joints
* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.