What Is Fat Embolism Syndrome?

Q:
What is fat embolism syndrome?

A:
Fat embolism syndrome (FES) occurs when embolic fat macroglobules pass into the small vessels of the lung and other sites.

Fat embolism will produce endothelial damage, and result in respiratory failure, cerebral dysfunction and a petechial rash.

The initial symptoms are probably caused by mechanical occlusion of multiple blood vessels with fat globules that are too large to pass through the capillaries.

Several causes can be traced like fractures (a closed fracture of a long bone), orthopaedic procedures, severe burns, bone marrow biopsy, fatty liver, massive soft tissue injury, liposuction, acute pancreatitis, osteomyelitis and so on.

Keywords: fat embolism; fat embolism syndrome

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