What Is GPA?

Granulomatosis with polyangiitis (Wegener’s) (GPA) is a rare disease of uncertain cause.

It is the result of inflammation within the tissues called granulomatous inflammation and blood vessel inflammation (“vasculitis”), which can damage organ systems. The areas most commonly affected by GPA include the sinuses, lungs, and kidneys, but any site can be affected.

GPA primarily affects the upper respiratory tract (sinuses, nose, trachea), lungs, and kidneys. Any other organ in the body can be affected as well.

The symptoms of GPA and their severity vary among patients. General signs of the disease may include: loss of appetite, weight loss, fever and fatigue.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.