What is lipodermatosclerosis?
Lipodermatosclerosis refers to a chronic fibrosing process of the skin or connective tissue that involves both lower legs.
According to Wikipedia, it is also known as “chronic panniculitis with lipomembranous changes”, “hypodermitis sclerodermiformis”, “sclerosing panniculitis” and “stasis panniculitis”.
Lipomembranous can be categorized into panniculitis, which is characterized by the inflammation of the panniculus adiposus, or subcutaneous adipose tissue.
There are no exact causes of lipomembranous. Some of the possible pathogenic factors may include:
- varicose veins;
- venous incompetence;
- venous hypertension;
- tissue hypoxia;
- leakage of proteins into the interstitium;
- leukocyte activation.
Lipomembranous is believed to occur most commonly in middle-aged women.