What Is Marfan Syndrome?

Marfan syndrome is a genetic disorder associated with the body’s connective tissue.

Put simply, this tissue connects all cells, organs and tissue throughout your body together, helping your body grow and develop properly.

Marfan syndrome occurs when the gene in charge of fibrillin-1 producing in your body get a mutation, increasing the transforming growth factor beta, or TGF-β.  And this TGF-β causes features of Marfan syndrome, mostly in the heart, blood vessels, bones, joints, and eyes.

Physical Traits in People With Marfan Syndrome

  • Long arms, legs, fingers, and toes and flexible joints
  • A tall, thin build
  • Scoliosis, or curvature of the spine
  • A chest that sinks in or sticks out
  • Crowded teeth
  • Flat feet

Generally, around 1 in 5000, men or women, have this disease. Also, it happens among all races and ethnic groups and 75% of the cases result from the genetic mutation.

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.