What is osteosclerosis?

What is osteosclerosis?

Osteosclerosis means abnormal hardening or eburnation of bone. Bone remodeling is a lifelong process in which bone tissue renews itself by replacing old tissue with new. People with this condition have a decreased level of a type of white blood cells. People who are suffering from osteosclerosis tend to be short in stature, and they normally have delayed growth.


The genetic defect or mutation that causes this condition is not yet known. However, prostate cancer, hemangioma and Erdheim-Chester disease could be some of the possible causes.


  • Frequent bone fractures and breaks
  • Bone pain
  • Short stature
  • Hypocalcemia (low levels of calcium in the blood)
  • Vision problems
  • Hearing problems


Most people with osteonecrosis need treatment. Your treatment options may be nonsurgical, surgical, or both.

Keywords: osteosclerosis;hardening;bone

* The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.